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doi: 10.1155/2017/7265238 27

Wszystkie dostpne dane pochodz wycznie z bada na zwierztach laboratoryjnych, ktre nie mog by bezporednio ekstrapolowane na ludzi bez waciwych bada klinicznych

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Benefits are often greatest in individuals with existing B12 deficiency or suboptimal methylation

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Patients who are particularly sensitive to GI side effects, who have a history of severe nausea with other medications, or who simply prefer a cautious approach may benefit from starting lower