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extreme tiredness (fatigue) shortness of breath chest pain or tightness problems with memory and concentration (brain fog) difficulty sleeping (insomnia) heart palpitations dizziness pins and needles joint pain depression and anxiety tinnitus, earaches feeling sick, diarrhoea, stomach aches, loss of appetite a high temperature, cough, headaches, sore throat, changes to sense of smell or taste rashes Ah

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5,6 The neuroprotective role of GSH against oxidative stress is well established

UCK2 inhibitors are still in preclinical development, but are positioned in combination with 5FU or other cytotoxics that alter nucleotide pools