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ATM-ESCO2-SMC3 axis promotes 53BP1 recruitment in response to DNA damage and safeguards genome integrity by stabilizing cohesin complex

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Patients should be encouraged to prioritize nutrient-dense foods and ensure adequate protein intake (typically 1.2-1.6 g/kg of ideal body weight daily during active weight loss, with higher amounts for those engaging in resistance training)

Comparison with atorvastatin binding to HMG-CoA reductase, its intended target, offers clues on how to modify the statin to reduce RyR1 binding, while leaving binding to HMG-CoA reductase unperturbed

Lupin, a nutritionally rich legume, is distinguished by its high protein concentration and favorable amino acid profile, particularly in lysine content [14]