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Despite its theoretical appeal for treating insomnia ( Dopamine plays a crucial role in the transition from nonrapid eye movement (NREM) sleep to rapid eye movement (REM) sleep through a transient increase in the basolateral amygdala (BLA), acting on D2 dopamine receptors to initiate the NREM-to-REM shift

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Acta Neuropathol Commun 4:87 Schenk DB, Koller M, Ness DK, Griffith SG, Grundman M, Zago W, Soto J, Atiee G, Ostrowitzki S, Kinney GG (2017) First-in-human assessment of PRX002, an anti--synuclein monoclonal antibody, in healthy volunteers

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