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Increased levels of miR-144 have been found in a subset of HbSS patients with typical severe anemia and reduced NRF2 protein levels, causing a reduction of GSH regeneration and impairing cell response to OS, thereby providing a possible mechanism for the increased anemia severity seen in these patients [221]

The exogenous antioxidants included -carotene, retinol, and vitamins B6, C, and E

Therefore, studies have explored the role of autophagy/apoptosis as a new target mechanism in domains such as chemo-resistant cancer therapy and toxicology

Many patients with ongoing issues like joint pain or inflammation experience long-term relief with regular peptide therapy

The cleavage of the scissile bond of substrates as oxytocin and vasopressin is anticipated to take place after a nucleophilic attack by water assisted by the carboxylate function of Glu465 in the active site of IRAP