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It should be mentioned that most of the subjects who experienced deterioration of kidney function with exenatide had at least one risk factor for developing kidney disease, such as cardiac failure, hypertension, or use of nephrotoxic drugs [140]

IAH increases the risk of Level 3 hypoglycaemia by sixfold [114] and may lead to the person with diabetes omitting insulin injections intentionally or loosening tight glucose management to prevent their occurrence

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