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The citrullination of epithelial neutrophil-activating peptide 78/CXCL5 chemokine by human peptidylarginine deiminase (PAD) present in the gut, has been reported to stimulate the production of monocyte recruiting chemokines and promote inflammation (Yoshida et al

FRMULA

Oral supplements are effective with doses starting at 2,000 mcg daily, followed by a decrease to 1,000 mcg daily, then weekly, and finally down to monthly

In cases of severe deficiency or pernicious anemia, injections may be given daily or weekly initially, followed by maintenance doses every month

Autotomy, where animals mutilate a denervated limb, is considered a behavioral marker of neuropathic pain

That structural similarity is what makes it so effective