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Because the two problems compound

Injecting Tirzepatide in the thigh is a common and recommended method, as the thigh offers a large, accessible area with sufficient fatty tissue for proper absorption

Dysuria, urinary frequency, urgency, suprapubic pain, or visible blood in the urine warrant medical evaluation, typically beginning with urinalysis and, when indicated, urine culture to confirm infection and guide antibiotic selection

doi: 10.1093/jnen/nlac034, 75

Its active ingredient, semaglutide, belongs to a class of medications called GLP-1 receptor agonists