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Additionally, side effects were uncommon, non-serious, and the risk did not significantly differ between antioxidant and placebo groups

In overweight/obese PCOS women with vitamin D deficiency, daily administration of 1,000 mg of calcium combined with 50,000 IU of vitamin D weekly for 8 weeks revealed that calcium supplementation, with or without additional vitamin D, resulted in significant diminutions in FBG, FINS, HOMA-IR, TG, and VLDL-C, along with a notable increase in the QUICKI (117)

International Journal of Molecular Sciences, 22

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Some people believe that you should wait to eat until you experience physical signs of hunger, assuming that listening to your body and eating less often will boost the medications effects