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In vitro hepatic models suggested that flavonoids and sulfur-containing compounds in garlic supplements might interfere with the activity of efflux drug transporters of the ATP-binding cassette (ABC) family, including P-glycoprotein, multidrug resistance protein (MRP), and breast cancer-resistance protein (BCRP), which function as ATP-dependent efflux pumps that actively regulate the excretion of a number of drugs limiting their systemic bioavailability

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Acknowledgements This study was funded by National Institutes of Health P50MH106438 and R01MH059883 grants awarded to C.S.C

It also supports a healthy immune system and healthy aging

Dose titration and monitoring protocols remain the same regardless of cholecystectomy history

Inhibition of the VEGF signaling pathway attenuates tumorassociated macrophage activity in liver cancer