Cavalieri EL, Stack DE, Devanesan PD, et al
doi: 10.1016/j.bioactmat.2023.10.002
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Administration is typically intravenous or intramuscular, which limits its accessibility compared to orally available or injectable peptides, but the clinical evidence supporting its use in serious neurological injury is stronger than that for almost any other peptide in this category
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Investigations into the neurobiological underpinnings of anxiety-like behaviors in AD models have suggested multiple factors, such as A deposition, Tau pathology, neuroinflammation, and neuronal or neurotransmitter changes