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It helps maintain mitochondrial membrane potential and prevent the release of pro-apoptotic factors from mitochondria, thereby preserving cell viability (Pang, 2015)
Am J Physiol Lung Cell Mol Physiol 292 : L824L832 Lee KS, Kim SR, Park HS, Park SJ, Min KH, Lee KY, Choe YH, Hong SH, Han HJ, Lee YR, Kim JS, Atlas D, Lee YC 2007 A novel thiol compound, n-acetylcysteine amide, attenuates allergic airway disease by regulating activation of nf-kappab and hypoxia-inducible factor-1alpha
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The multi-faceted mechanisms of polyphenols, ranging from gut microbiota modulation to their involvement in immunometabolic pathways and epigenetic reprogramming, indicate they are not simply antioxidants but complex biological response modifiers (10, 14)