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Trimethyllysine Hydroxylase Epsilon (TMLHE), an KGDD, is the first and rate-limiting step in de novo carnitine synthesis but no studies to date have characterized how changes in KG affect carnitine synthesis or carnitine-dependent processes
It's frequently seen in atopic dermatitis patients and patients with very dry skin
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PatikornCRoubalKVeettilSChandranVPhamTLeeYet alIntermittent fasting and obesity-related health outcomes: An umbrella review of meta-analyses of randomized clinical trials
Most of the mutations are leaky so that many patients have residual enzyme activity
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