Genetic Predispositions and Individual Maintenance Dose Response Research increasingly shows that genetic variants in GLP-1R, GIPR, FTO, and MC4R pathways influence how individuals respond to GLP-1 maintenance therapy
doi: 10.1016/j.mce.2021.111239 14 GordanRGwathmeyJKXieLH
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However, given the associated risks of cardiovascular disease and various cancers, the benefits of these medications, such as better glycemic control, weight loss and improvement in cardiometabolic risk factors as well as other obesity complications, appear to outweigh the risks for most adults with obesity [143, 153]
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