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germ-free or antibiotic-treated mice had impaired microglial clearance of A plaques, which could be restored by supplying acetate [100]
Over time, this chronic immune activation may contribute to fatigue, cognitive changes, digestive disruption, respiratory symptoms, metabolic instability, and heightened inflammatory sensitivity
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meningitidis is a naturally transformable species, its population is structured into rather stable clonal complexes (ccs), which cluster genetically associated sequence type (ST) strains defined by multi-locus sequence typing (MLST) of seven conserved housekeeping genes (Maiden et al., 2013)
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