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This inhibition leads to reduced steatosis and improvement of insulin sensitivity [42]

Specifically, there was an increase in the endoplasmic-reticulum-to-cytoplasm Zip7 mRNA and protein expression as well as phosphorylation, leading to elevated intracellular free zinc levels

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In the lungs, inflammation commonly leads to increased airway resistance (due to bronchoconstriction and increased mucous production) and decreased lung compliance (due to increased collagen deposition in the parenchyma and immune cell infiltrates)