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[DOI] [PMC free article] [PubMed] [Google Scholar] 50.Tohgo A, Pierce KL, Choy EW, Lefkowitz RJ, Luttrell LM

Abstract Ferroptosis is a non-apoptotic cell death regulated by iron-dependent lipid peroxidation

Safety Reported side effects are generally mild: injection-site pain, transient headaches, nausea, and occasional mood shifts

July 2324, 2026 meeting of the Pharmacy Compounding Advisory Committee

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To test the effect of Sp in paraquat-induced oxidative stress model, seven days old wild type flies, constitutively expressing mitochondrial (mt)-roGFP, were exposed to 10 mM paraquat for 24 h and then co-treated with 2.5 mM Sp for 24 h, prior to roGFP fluorescence estimation