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Core molecular machinery governing ferroptosis The pro-ferroptotic axis: iron, lipids, and oxidative damage Iron homeostasis in ferroptosis Iron is one of the most important metallic elements in living organisms

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ASK1 is activated in response to oxidative stress and heat shock

However, the physical or biochemical drivers responsible for the transition from a reducing to oxidizing environment remains up for debate (Olejarz et al

Interestingly, Waldron et al

& Mooseker, M