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The timeline is almost comparable whether you choose GHK-Cu topical vs injection options, since research shows injected GHK-Cu has poor bioavailability

The fundamental technique is identical

in seven healthy volunteers reported no significant increase in plasma glutathione levels for up to 270 min

If you are deficient in vitamin B12, improvement in symptoms such as tiredness may begin within days to weeks after starting injections

However, its long-term safety and possible unpleasant adverse effects in humans are not fully understood