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Cumulative incidence curves stratified by GLP-1 RA type were generated using time-to-onset data, excluding reports with implausible (onset 0 days) or missing event dates (Table S4)
Others experience anxiety about loose skin, about how others perceive their changing body, or about whether they deserve to look different

Contact your healthcare provider promptly if you experience: Severe or persistent abdominal pain , particularly if radiating to the back or accompanied by vomiting, as this may indicate pancreatitis (a rare but serious side effect) and requires urgent medical attention (call NHS 111, visit A&E, or call 999 if severe) Signs of gallbladder problems , including pain in the upper right abdomen, fever, or yellowing of skin or eyes (jaundice requires urgent assessment) Persistent nausea or vomiting that prevents adequate food or fluid intake, risking dehydration Symptoms of hypoglycaemia (if you have type 2 diabetes and take other glucose-lowering medications), such as shakiness, confusion, or excessive sweating Unexplained changes in bowel habits lasting more than a few days Difficulty swallowing or persistent heartburn , which may indicate delayed gastric emptying If you have type 2 diabetes, report any new or worsening visual symptoms promptly, as semaglutide may be associated with diabetic retinopathy complications

In the UK, probiotics are regulated as food supplements rather than medicines, meaning quality can vary considerably
In turn, this gives your body time to adjust and also helps minimize side effects, such as nausea