Supports bodily functions, tissue repair, and protein synthesis
DSB detection was based on expression levels of -H2AX, a classic biomarker for DSBs, which could be visualized by immunofluorescence microscopy
HT1080 cells were treated with 10 M of erastin for 0, 6 and 24 h before harvesting
To investigate whether albumin could be engineered to evade L585 cleavage and the resulting reduction in FcRn binding, we constructed a panel of 18 full-length 585-engineered human albumin variants, in which the C-terminal leucine residue was substituted with each of the other naturally occurring amino acids, except for cysteine (Fig
( A ) Mouse caSMCs were transfected with a combination of 4 MTP-specific siRNAs, and relative Mtpa mRNA expression was measured by reverse transcription PCR versus control siRNA
doi: 10.1016/j.taap.2014.01.004