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The result is often skin that appears looser, less defined, or lacking the structural integrity it once had particularly around the jawline, neck, cheeks, and brow

The reality check: retatrutide is still investigational

PMID 23397029

Like semaglutide, tirzepatide was initially developed as a treatment for type 2 diabetes but has also been found to promote weight loss

Other available weight loss treatments include Orlistat and Xenical

More concerning reactions requiring immediate medical attention include severe persistent abdominal pain potentially indicating pancreatitis, symptoms of allergic reactions including rash, itching, or difficulty breathing, or signs of hypoglycemia such as excessive sweating, confusion, or rapid heartbeat