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The compound of any one of claims 1 to 6 wherein L comprises a divalent polyglutamic acid radical, where at least one glutamic acid forms an amide with an aminopolyhydroxy radical
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Up-regulation of mGlu2 receptors was observed in cultured DRG neurons isolated from 30-day acetyl-l-carnitine-treated -GalA knockout mice, which was no longer detectable in DRG neurons isolated 30 days after the end of treatment, hinting at an additional mechanism being responsible for the long-term analgesic effect [35]
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Cell Adhes Migr 8, 440451.CrossRefGoogle Scholar Mohammed, BM, Fisher, BJ, Kraskauskas, D, et al