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The process involves: Dissolution in the stomach Binding to intrinsic factor Absorption in the ileum (small intestine) Transport through bloodstream to tissues With proper oral B12 dosage, supplementation can gradually restore normal levels, especially in cases of dietary deficiency
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Folic acid is reduced by enzymes folate reductase and dihydrofolate reductase and forms dihydrofolic acid tetrahydrofolic acid respectively
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Such reports are vulnerable to selection bias, missing comparison groups, inconsistent product characterisation and incomplete adverse event detection
Cell 49 , 118129 (2019)
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