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Abstract Cystinotic patients have been shown to excrete in their urine high levels of pyroglutamate, an intermediate metabolite of the adenosine triphosphate (ATP)dependent -glutamyl cycle, which is responsible for glutathione (GSH) synthesis

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Patients are often advised to avoid trigger foods, maintain a healthy weight, and elevate their heads while sleeping to minimize symptoms

Han, F., Li, S., Yang, Y