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Oxygen (O 2 ) is essential for life and plays a crucial role in many biological processes [23] and, given to its high oxidation-reduction (redox) potential, it is an ideal electron acceptor

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390 Using oxamate and PD-1 blockade pembrolizumab stimulated CD8 + T cell infiltration and hindered tumor proliferation in humanized mouse NSCLC model, thereby sensitizing immunotherapy