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Notably, increased levels of Alistipes and reduced butyrate-producing Faecalibacterium are emerging as potential diagnostic biomarkers [28]

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Specifically, altered microbiota composition can disrupt dopamine metabolism and subsequently interfere with thyroid-stimulating hormone (TSH) secretion via the hypothalamicpituitary-thyroid axis, further complicating thyroid homeostasis (Xie et al., 2023)