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Several Phase 3 trials cover type 2 diabetes (TRANSCEND-T2D), obstructive sleep apnea, MASLD, chronic kidney disease in patients with type 2 diabetes, knee osteoarthritis (TRIUMPH-4), and cardiovascular outcomes

Requena T, Martnez-Cuesta MC, Pelez C (2018) Diet and microbiota linked in health and disease

These findings support its potential as a scalable, population-level cardiometabolic intervention and highlight the need for system-level strategies to enhance access and uptake

Although the drug carries a steep price, some analysts have anticipated it will become the best-selling drug in history

Mean age was 73.6 years for all participants and ranged from 73.1 to 74.7 across treatment groups