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doi: 10.3389/fendo.2023.1133000 Received 28 December 2022 Accepted 13 March 2023 Published 24 March 2023 Volume 14 - 2023 Edited by Silvia Martina Ferrari, University of Pisa, Italy Reviewed by Sabrina Rosaria Paparo, University of Pisa, Italy

Proinflammatory cytokines, such as tumor necrosis factor-alpha (TNF-), interleukin-1 beta, and interferon-gamma (IFN-), promote ROS production, while ROS scavengers such as pyrrolidine dithiocarbamate and N-acetyl-cysteine (NAC) can reduce the ROS levels induced by these cytokines 14

+ - 5 amino 1 mq is a laboratory-grade research chemical provided as a high-purity powder

MAPK Pathway Modulation p38 MAPK pathway suppression significantly inhibits LPS-induced phosphorylation, reducing inflammatory response and cellular stress

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This investigation examined many human and animal scientific studies