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Lactate dehydrogenase assay Cell death was measured by the release of lactate dehydrogenase (LDH) into the culture medium

Commun Biol 8 , 791 (2025)

Even though GSH levels were below the threshold for rescuing WT cell growth in cystine-free conditions, co-culturing with GGT1 + cells led to complete rescue of WT cell growth (Fig

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i Also, it has been reported that acetaminophen poisoning is involved in nearly 50% of patients in the U.S

42 Ferroptosis is initiated by the depletion of GSH, leading to the inactivation of GPx4, a key enzyme that protects against lipid peroxidation