Mazdutide, was designed by Innovent (Originally IBI362) to mimic OXM but had chemical modifications to extend its half-life , to around 7.5-9.8 days [30]
In peptide research, a "stack" simply means two or more compounds used together rather than alone
Medications called GLP-1 receptor agonists (GLP-1 RAs) mimic this hormones effect
In addition to being recognized for its ability to boost weight loss efforts - research is also showing its promise in reducing inflammation - making it the perfect addition to any weight control formula
And in 2025, Wegovy also received FDA accelerated approval for the treatment of noncirrhotic metabolic dysfunction-associated steatohepatitis (MASH) with moderate to advanced liver fibrosis, underscoring that these medications can impact disease processes well beyond body weight alone
For those taking insulin or sulfonylureas, this may increase hypoglycaemia risk, requiring medication review