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1.3 ROS and autophagy interplay Autophagy is a catabolic process that is responsible for the degradation of intracellular proteins and damaged organelles in response to endogenous and exogenous stresses, including oxidative stress, endoplasmic reticulum stress, hypoxic stress, and nutrient and growth factor starvation (Galati et al., 2019)

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The pathophysiology is thought to involve increased sensitivity to cholecystokinin (CCK), leading to excessive gallbladder contractility

In rabbit models with critical-sized mandibular bone defects, the application of M