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3.2 Lipid peroxidation in cancer pathophysiology Free radical mediated lipid peroxidation which is the oxidative breakdown of lipids is one of the important events that govern cancer development [56]

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It is used to reduce adipose tissue because it is responsible for the transport of fatty acids to the mitochondria, thanks to which it is possible to produce energy and use the reserves of adipose tissue accumulated in the body

ROS accumulation also induces mitochondrial DNA lesions, strand breaks, and DNA degradation (42)

They need to be delivered in the right medium and at the right concentration to penetrate the skin

Oberholzer HM, van der Schoor C, Bester MJ (2015) Sibutramine, a serotoninnorepinephrine reuptake inhibitor, causes fibrosis in rats