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This introduces clinical heterogeneity and considerably attenuates the practical interpretation of pooled estimates, given the well-established beneficial effects of GLP-1 RAs in reducing both HbA 1c and body weight, as opposed to the neutral effect of a placebo intervention [4,5,6]

Pharmacol Rep 2006 MayJun

Over 3 years, 45 people needed to be treated to prevent one major CV event and 39 needed to be treated to prevent one death

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Benefits may include weight loss, improved blood sugar control, reduced cardiovascular risk factors, increased energy, and in some cases improved testosterone levels and sexual health.