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Dysbiosis contributes to fibrogenesis in the course of chronic liver injury in mice (in Eng)
Ascorbic acid directly scavenges superoxide anions, hydroxyl radicals, and other free radicals, and regenerates antioxidants such as vitamin E and GSH
Another advantage of lomustine is that it can be administered orally, although we used intraperitoneal injection in our study to deliver an exact dose of lomustine to mice
Correspondingly, we found that the NAC treatment largely increased the number of surviving SGNs in the peroxynitrite + NAC group compared with the peroxynitrite-only group, as well as in the peroxynitrite + gpx1 / + NAC group compared with the peroxynitrite + gpx1 / group (Figure 6D)