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NO-releasing agents, such as JS-K ( O 2 -(2,4-dinitrophenyl)-1-[(4-ethoxycarbonyl)piperazin-1-yl]diazen-1-ium-1,2-diolate) 123 and PABA/NO ( O 2 -[2,4-dinitro-5-( N -methyl- N -4 carboxyphenylamino)phenyl] 1- N , N -dimethylamino)diazen-1-ium-1,2-diolate) 124 , are able to induce differentiation and cell death in a variety of cancer cells through GSH consumption, DNA synthesis inhibition and inhibition of enzymes involved in the defense against cell damage

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To put this amount into perspective, a healthy diet rich in fresh fruit and vegetables may provide about 150 mg of preformed glutathione per day

The FDA regulates pharmacy compounding under the Federal Food, Drug, and Cosmetic Act, with section 503A covering traditional compounding pharmacies

Hamza T, Barnett JB, Li B