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Heavier or lighter bleeding: Semaglutide may also impact the flow of menstrual blood, leading to changes in bleeding patterns

The landmark SUSTAIN-6 trial , published in The New England Journal of Medicine , found that Semaglutide significantly reduced the risk of major adverse cardiovascular events (such as heart attack, stroke, or death from cardiovascular causes) in patients with type 2 diabetes who were at high cardiovascular risk

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And repeated trauma to the same area increases inflammation and discomfort

While there is no direct pharmacological interaction between semaglutide and levothyroxine, Wegovy's effect on gastric emptying could potentially affect absorption of oral medications