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Critical limitations identified in the systematic review include predominant use of small rodent models (primarily rats), short follow-up periods relative to human healing timelines, variable dosing regimens complicating dose-response assessment, and lack of standardized outcome measures across studies

Most of what we know comes from preclinical and experimental research, rather than human trials

presented a pH/reduction-sensitive carboxymethyl chitosan nanogel (CMCSN) modified by targeting peptide angiopep-2 (ANG) and loading with doxorubicin (DOX) named DOX-ANG-CMCSN

Candida albicans infection affords protection against reinfection via functional reprogramming of monocytes

These compounds also interact with immune receptors and stimulate cellular responses that promote immune surveillance and pathogen clearance

5-Amino-1MQ enhances mitochondrial energy and NAD+ to drive metabolism