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The Wegovy SmPC lists the following as occurring in more than 1 in 10 patients on the 2.4 mg dose [1] : nausea (44% on semaglutide vs 16% on placebo), diarrhoea (30% vs 16%), vomiting (24% vs 6%), constipation (24% vs 11%), and abdominal pain

(a,c)Differ from the healthy subjects

Close monitoring during the first 48 weeks helps manage side effects and guide dose adjustments

Those struggling with meal planning or nutritional adequacy should consider requesting a referral to a registered dietitian nutritionist (RDN) for personalized guidance

Contraindications and Restrictions

Nowadays, the application of FMT in anti-osteoporosis treatment remains in the research stage and has not yet been applied in a clinical setting