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In this context, it has been demonstrated that the restoration of -cell mass can occur not only through proliferation of existing -cells but also via transdifferentiation of other pancreatic cell types, such as -, -, PP-, and ductal epithelial cells (Figure 1B)

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Attempts to directly test the dogs color vision have had mixed results

doi: 10.1038/s41467-018-05861-7

One route involves the hydrolysis of cytoplasmic CE by neutral cholesterol esterase and the resulting free cholesterol is mobilized away from the ACAT pool (72,73) and made available for efflux via ABCA1, ABCG1, SR-BI, and aqueous diffusion (Figure 2)

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