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One can do this by lightly exfoliating the bikini area before application

doi: 10.1042/BJ20081151

The AP-1 transcriptional complex: local switch or remote command

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G., Glutathione Peroxidase1 Gene Knockout on Body Antioxidant Defense in Mice, BioFactors 14 (2001): 9399, 10.1002/biof.5520140113

Formulations designed to enhance the bioavailability of lipophilic and/or poorly absorbed supplements act mechanistically through modifying these factors (McClements et al., 2015)