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In clinical trials (the SUSTAIN series of studies), weekly semaglutide led to significant drops in hemoglobin A1c (a marker of long-term blood sugar) compared to both placebo and other diabetes medications

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In just a few months, I added over 25 pounds to my bench, squat, and deadlift PRs

It works by activating both the glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptors

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The critical factor is maintaining peptide concentration between 1025mg/mL for optimal stability concentrations above 30mg/mL increase aggregation risk, while dilutions below 5mg/mL accelerate oxidative degradation during the 28-day refrigerated storage window