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MGF E-domain, by contrast, keeps satellite cells in a proliferative state, expanding the myogenic precursor pool before differentiation signals (from IGF-1Ea/systemic IGF-1) later trigger commitment and fusion

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High-resolution confocal microscopy was performed with a Leica TCS-SP2 confocal system equipped with Ar/Kr and He/Ne continuous wave lasers for excitation at 488 nm and 546 nm, respectively

Even when the injury is not severe enough to require surgery, recovery can be slow, especially when tendons, ligaments, fascia, and other connective tissues are involved