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But GLP-1s are not a crutch or a form of cheating

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Recent research shows that bitter substances that activate TAS2R38 can also increase glucagon-like peptide 1 release.[ref] Related article : Bitter Taste Receptors Berberine: One bitter substance that activates TAS2R38 is berberine .[ref] Berberine is readily available as a supplement and also impacts blood glucose levels

Although most incidents involved accidental dosing or therapeutic mistakes rather than intentional misuse, the sheer size of the increase surprised the research team