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Patients may develop executive dysfunction, slowed processing speed, gait instability, mood changes, or urinary symptoms over many years

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The Foundation 5 of recovery includes eating right, sleeping right, moving right, talking right, and pooping right (29:53) Sleep restoration is the top priority, followed closely by gut health and microbiome balance

Glutathione is also the obligate substrate for glutathione S-transferases (GSTs), the enzyme family responsible for phase II hepatic detoxification conjugating GSH to electrophilic xenobiotics, heavy metals, and endogenous toxins to render them water-soluble and excretable

Consequently, use of a diagnosis of single cell necrosis is appropriate based strictly on H&E staining

I., Moberg, M., Bergquist, J