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Patients with mild to moderate renal impairment generally do not require dose adjustment, but closer monitoring may be warranted, particularly for signs of gastrointestinal adverse effects that could lead to dehydration and worsening renal function

As we talk, she marvels that she's had a box of chocolates on her desk all day that she still hasn't touched, which is probably the result of both the drug and a psychological shift, since she hasn't been taking the injections that long

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p = 0.04), indicating a notable advantage of Tirzepatide over Semaglutide in reducing HbA1c levels, with a large difference in efficacy between the two medications (Figure 10)