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Novo Nordisk is currently running two large Phase 3 trials to investigate the effect of GLP-1 drugs on Alzheimer's disease, based on early data suggesting reduced neuroinflammation, improved cognition and function, and enhanced memory, as well as trials in which GLP-1 drugs appeared to substantially reduce dementia rates in diabetes patients

Excess B 12 beyond the blood's binding capacity is typically excreted in urine

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Nakhaei K, Ishijima M, Ikeda T, Ghassemi A, Saruta J, Ogawa T