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When used together, they target complementary biological systems cellular energy production and oxidative stress defense which is why many clinicians consider them as part of a combined approach under medical supervision

Increment in carotid IMT of more than 0.34 mm/year can lead to a cardiovascular event with first myocardial infarction and stroke can happen with a carotid IMT above 0.882 mm and 0.75 mm, respectively 47