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Gastrointestinal distension by pectin-containing carbonated solution suppresses food intake and enhances glucose tolerance via GLP-1 secretion and vagal afferent activation

The remarkable commercial success of drugs like semaglutide and tirzepatide has created strong market momentum, driving significant investment in next-generation molecules and accelerating development cycles

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As noted above, bupropion is FDA-approved to treat major depressive disorder (MDD) and seasonal affective disorder (SAD), and under the brand name Zyban, it is also approved as a smoking cessation aid