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For an expensive medication with real health implications, that is a risky bet
In human studies, ipamorelin administered at GH-releasing doses produced dose-dependent GH secretion without significant changes in cortisol, ACTH, prolactin, FSH, LH, or TSH
Even with B12 in your tirzepatide injection, you may need additional supplementation or more frequent blood level monitoring
So, in summary: FOXO4-DRI appears to represent the next-generation senolytic, offering improved specificity, but it is still earlier stage than many small-molecule senolytics or repurposed drug combinations
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